Anterior uveitis and severe keratoconjunctivitis sicca in a patient with steroid-induced ocular hypertension - Case Report

Abstract

Severe dry eye syndrome and anterior uveitis are known as adverse effects of different intraocular pressure (IOP) lowering drops. We report a case of acute anterior uveitis and severe keratoconjunctivitis sicca associated with combined IOP-lowering therapy including GANFORT® and SIMBRINZA® in a patient with steroid-induced ocular hypertension. 360-degree selective laser trabeculoplasty (SLT) was performed in both eyes as an IOP-lowering treatment. The transition from combined IOP-lowering therapy to monotherapy and significant reduction of ocular side effects combined with improved ocular surface as well as patient’s quality of life. The appropriate treatment regimen to reduce elevated IOP should be individualized, considering multiple topical adverse effects related to glaucoma treatment. SLT is a proven clinically effective procedure and a valuable potential alternative as primary or adjunct treatment that should be definitely considered in patients with ocular hypertension and severe intolerance to topical medications.