A typical features in Irvan syndrome demonstrated on multimodal imaging

Hashim Ali   Khan; Muhammad Aamir Shahzad; Muhammad Amer Awan

doi:10.30546/2788-516X.2021.2.1.5

Hashim Ali Khan SEHHAT Foundation Hospital
Muhammad Aamir Shahzad Aziz Fatimah Medical and Dental College
Muhammad Amer Awan Shifa International Hospital

DOI: https://doi.org/10.30546/2788-516X.2021.2.1.5

Keywords: IRVAN syndrome, Multimodal imaging, Neuroretinitis, OCTA in IRVAN syndrome, Retinal Vasculitis

Abstract

Purpose: The purpose of this work was to describe idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome in a 32-year-old male.

Methods: Case report.

Case report: A 32-year-old male presented with acute visual disturbance. Multimodal imaging revealed retinal vasculitis, aneurysms and neuroretinitis in addition to vitreous inflammation, retinal ischemia and epiretinal membrane. Optical coherence tomography angiography (OCTA) demonstrated multiple microaneurysm in both eyes.

Conclusion: Multimodal imaging was helpful in diagnosing and differentiating IRVAN syndrome from other similar- looking clinical entities. Retinal aneurysms and retinal ischaemia were detectable by fundus fluorescein angiography (FFA). However, OCTA showed multiple microaneurysms that were not clearly differentiable by FFA because of vitreous inflammation and vascular leakage .Microaneurysms in IRVAN syndrome area previously unreported observation. OCTA may help detect thesechanges with accurate details.

Author Biographies

Hashim Ali Khan, SEHHAT Foundation Hospital

OD, FAAO, (Corresponding Author) SEHHAT Foundation Hospital, Main KKH, Danyore, Gilgit, Pakistan

Muhammad Aamir Shahzad, Aziz Fatimah Medical and Dental College

MBBS, FRCS Aziz Fatimah Medical and Dental College, Faisalabad, Pakistan

Muhammad Amer Awan, Shifa International Hospital

FRCS, FRC Ophth, Shifa International Hospital, Islamabad, Pakistan